On the NHS, Wegovy is typically prescribed within specialist weight management services according to NICE guidance (TA875), which has stricter eligibility criteria than the marketing authorisation (for most adults, BMI 35 kg/m with a weight-related comorbidity, with adjustments for certain groups)
Until the FDA issues specific guidance defining the comparability standard for autologous C&G therapies (a process that will require substantial scientific input from industry, academia, and patient advocacy groups), the BPCIA pathway for C&G therapy biosimilars remains operationally undefined
Use in Special Populations Pediatric population: The safety and efficacy of Semaglut in children and adolescents below 18 years have not yet been established
The hypothalamus is a part of the brain focused on regulating daily functions like hunger, body temperature, heart rate, and more