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Source: Novo Investor Day 2022 Estimating the costs associated with diseases are inherently imprecise and noisy due to difficulties in normalising the difference between individual circumstances and lifestyles, but for the sake of providing ball-park figures, some studies have found that excess medical spending on obesity for adults is around 260 billion USD or around 1800 USD excess per person in 2019

Mitochondrial DNA in liver inflammation and oxidative stress

Waters high specific heat ( 4.184 J/gC ) slows temp change rates by 55%

This hypothesis is further supported by the results of bivamelagons phase II trial in patients with HO, where bivamelagon was able to achieve BMI reductions comparable to setmelanotide (NCT06046443, NCT07156578) (103, 104)