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Fluid retention occurred in 32% of women with axillary node-negative, estrogen-receptor positive breast cancer who received adjuvant tamoxifen (n = 1422) compared with 30% of women who received placebo (n = 1437) following primary surgery in a randomized, double-blind study (the NSABP B-14 study)

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Weight Loss Potential Early Retatrutide clinical trials have shown noticeable weight reduction, with higher doses producing results that attracted attention in obesity research

Warnings Benzyl Alcohol: Patients who have early Leber's disease (LHON) a hereditary disease that causes optic nerve atrophy have been found to suffer severe and swift optic atrophy when treated with vitamin B12