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Epidemiology of type 2 diabetesglobal burden of disease and forecasted trends

Standard versus slow retatrutide titration protocol: both reach 12mg, but the 6-week conservative path takes approximately 6 additional weeks

While GLP-1 receptors are expressed primarily in pancreatic beta cells, the gastrointestinal tract, and certain areas of the central nervous system, the expression and function of these receptors in joint tissues is not well characterized

Phase 3 trials are currently ongoing (see ClinicalTrials.gov for the retatrutide Phase 3 programme), and these larger studies will provide more robust data on the long-term safety and tolerability of retatrutide across more diverse populations