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Finally, propensity score is only appropriate when the strongly ignorable treatment assignment assumption is satisfied 24

Insurers are basing their coverage decisions, in part, on rebates, discounts that are offered by drugmakers as a negotiating chip to persuade insurers to cover one product over a competitor

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Karuna indicated before launch that it anticipated NCE exclusivity for Cobenfy, arguing that because xanomeline had never previously received FDA approval as a drug product, the xanomeline component qualified as a new active moiety under 21 CFR 314.108(b)(2)