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When medication is appropriate, the discussion should include: The limited evidence for GLP-1 agonists specifically in BED FDA-approved alternatives, including lisdexamfetamine Realistic expectations about outcomes and timeline Potential side effects and monitoring requirements Cost considerations and insurance coverage The importance of combining medication with behavioral interventions Monitoring during treatment should be systematic and multifaceted

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Starting treatment within 48 hours of symptom onset maximizes effectiveness while potentially increasing side effect intensity during the first 2-3 days of the 5-day course

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