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1,000 mg Coenzyme Q10 (CoQ10)

Jardiance may not be suitable for an individual who finds daily pill-taking overwhelming, and Ozempic may be a nice alternative due to its less frequent injection administration of once weekly

Acknowledgements We are grateful to Wenxin Li, Wenbo Feng, Chenyu Ye, Yingna Xu, Yan Chen, Xianyue Chen, Jiahui Yan and Qiuying Wang for technical assistance

The preservation of the active site architecture, notably the cysteine residue at position 36 (Cys 36 ), coupled with the marked reduction in enzymatic activity exhibited by the GpoA Cys36Ala variant relative to the wild-type enzyme, provides compelling biochemical support for the essential role of this residue in mediating GpoAs peroxidase function