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Antihistamines Promethazine (Phenergan) is used to relieve nausea and vomiting, though, it can also be helpful in easing restlessness

Amphetamines disrupt VMAT2 function and vesicular uptake through a combination of mechanisms: The Weak Base Effect (pH Gradient Collapse) : Amphetamines are lipophilic weak bases (pKa of 9.9) that can readily diffuse across both the plasma and vesicular membranes to accumulate inside synaptic vesicles (Wimalasena 2011)

Verify with your specific programme rather than from a general summary

Potentiation of opioid analgesia in dopamine2 receptor knock-out mice: evidence for a tonically active anti-opioid system