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The neuroactive steroid allopregnanolone suppresses hypothalamic gonadotropin-releasing hormone release through a mechanism mediated by the gamma-aminobutyric acidA receptor
Its an autoimmune disease in which the immune system produces antibodies that attack the thyroid, causing fibrosis or scarring of the thyroid tissue ( Hashimotos disease is associated with a variety of symptoms, including weight gain, fatigue, hair loss, anemia, constipation, cold intolerance, joint pain, dry skin, mood changes, difficulty concentrating, and more ( In addition to medication, diet and lifestyle modification can help reduce thyroid damage and improve symptoms and overall quality of life in people with Hashimotos
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