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The rationale is that metformin's insulin-sensitizing effects and modest appetite-suppressing properties may help prevent weight regain if the tirzepatide dose is reduced or eventually discontinued

Citations Citations to this article as recorded by Large-scale profile study on hepatitis B surface antigen levels in chronic hepatitis B: implications for drug development targeting functional cure Rex Wan-Hin Hui, Trevor Kwan-Hung Wu, Karen Cheuk-Ying Ho, Ryan Hin-Man Leung, Matthew Shing-Hin Chung, Danny Ka-Ho Wong, James Fung, Wai-Kay Seto, Lung Yi Mak, Man-Fung Yuen Gut .2026