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Instead, researchers aimed to replicate certain aspects of the disease process to study its mechanisms and test potential therapeutic approaches

While the mechanistic data for how LDN and these specific peptides work is strong and growing, large-scale, double-blind clinical trials for their combined use in Hashimotos are still lacking

However, NICE guidance emphasises that pharmacological treatment should form part of a multicomponent weight management programme including dietary modification and behavioural support

Briefly, the mice were randomly assigned to one of four treatment groups, and C6-labeled liposomes were injected via the tail vein