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Expression of pancreatic endocrine markers by mesenchymal stem cells from human umbilical cord vein

Each member of the treatment groups received an icv injection of scopolamine hydrobromide (70 nmol in 2 aCSF over a duration of 20 s) 20 min prior to testing followed by Nle'-AnglV or one of the analogs (in 2 aCSF) 5 min prior to testing

The incidence of any DR was 15.6 (95% confidence interval [CI], 14.3 to 16.8) events per 1,000 person-years in SGLT2i group and 19.3 (95% CI, 17.3 to 21.3) events per 1,000 person-years in GLP1-RA group, and the rate of any DR (subdistribution hazard ratio [SHR], 0.90

Rigid linkers are used when there is a requirement to preserve the spatial distance between the domains and their independent functions