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The same mechanism likely intensifies under afterload, as in obstructive HCM

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Hematoxylin and Eosin (H&E) and Immunohistochemical (IHC) Staining Formalin-fixed and paraffin-embedded rats pancreatic tissue sections were deparaffinized in xylene and rehydrated using graded ethanol into PBS

For example, sulforaphane reduced contrast agent-induced kidney damage in rats by increasing Nrf2 nuclear translocation and upregulating the expression of HO-1 and NQO-1 (13)