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These achieve substantially greater LDL reductions than the modest 17% decreases observed with GLP-1 receptor agonists

Figure 1 Discussion In the presented case of a newly diagnosed patient with type 2 diabetes, euDKA occurred at the very early onset after initiation of combined therapy with GLP-1RA and SGLT2i, in the absence of infection or other precipitating factors (such as alcohol overdose, pancreatitis, pregnancy), and proved refractory to standard therapy with insulin, glucose, and fluid resuscitation

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While the move should reduce spending in the near term, it will disrupt employees already taking medications like Zepbound and Wegovy, forcing many to seek alternative access routes to maintain treatmentmost notably via the cash-pay market