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Five out of 24 ME/CFS patients and 6 out of 25 long COVID patients were taking antidepressant medications

While lysosomotropic compounds may also directly stimulate autophagy, thereby causing increases in LC3-II in combination relative to compound alone, the autophagy enhancing may also represent adaptive change due to lysosomal dysfunction and without restoring lysosomal function

Treating with 5-amino-1MQ improved grip strength better than exercise alone in aged mice