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AsA is highly sensitive to light, heat, transition metal ions, and pH (alkaline conditions), causing DHA to permanently hydrolyze to generate 2, 3-diketogulonic acid and other non-damaging and non-radical compounds

Antimicrobial shield Platelets release antimicrobial peptides (like thrombocidins) and leukocytes in PRP add immune factors

It is also worth noting that the impact of CBS on tumor growth and progression is context-dependent, with CBS functioning as an oncogene in colon, ovarian and breast cancer but as a tumor suppressor in liver cancer 62,64

The protective effect of lithocholic acid on the intestinal epithelial barrier is mediated by the vitamin D receptor via a SIRT1/Nrf2 and NF-B dependent mechanism in Caco-2 cells