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[1] Licensed pharmacological options in the UK include orlistat (available at BMI 30 kg/m, or 28 kg/m with weight-related risk factors) and semaglutide (available within specialist weight management services as per NICE TA875, with adjusted BMI thresholds for some ethnic groups)

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For example, in Canada, attention is already shifting towards newer entrants like tirzepatide (Mounjaro/Zepbound), which has demonstrated superior efficacy in weight loss in the head-to-head SURMOUNT-5 trial iii and is gaining momentum

Singh - Glutathione: A marker and antioxidant for aging - VOLUME 140 - DECEMBER 01, 2002 - ISSUE 6 : P380-381 Jason Allen, Ryan D