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JHR symptoms include fever, chills, nausea and vomiting, headache, tachycardia (fast heartbeat), hypotension, and hyperventilation 1

In this study, long-term administration of rotenone in C57BL/6 mice triggered marked oxidative stress in the brain

Long et al., 2024), including the NADPH/FSP1/CoQ10 pathway, the dihydroorotate dehydrogenase (DHODH) pathway, the GTP cyclohydrolase 1 (GCH1)/tetrahydrobiopterin (BH4)/dihydrofolate reductase (DHFR) pathway, the membrane-bound O-acyltransferase 1/2 (MBOAT1/2) pathway, the peroxiredoxin 6 (PRDX6) pathway, and the 7-dehydrocholesterol (7-DHC) pathway

The incidence and prevalence of thyroid autoimmunity