how to switch from liraglutide to semaglutide vs Semaglutide: Comparing Weight Loss & Other Benefits Sankey Plot of Glucagon-Like Peptide-1

The article's table puts tirzepatide in a weaker evidence position, with no human lactation data at all versus minimal human data for semaglutide, and describes the usual provider approach as avoiding it

Unlike the weight loss drugs of ages past, GLP-1 agonists are safe and effective, even long term

Incretin Hormones Orally ingested glucose stimulates insulin secretion to a greater degree than intravenously administered glucose, a phenomenon labeled the incretin effect

Mounjaro (tirzepatide) and Victoza (liraglutide) are both FDA-approved to treat type 2 diabetes, while Zepbound (tirzepatide) and Saxenda (liraglutide) are FDA-approved specifically for weight loss