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Many studies have questioned if an increase in maternal folate during pregnancy, with the main aim of reducing neural defects, could somehow be related to an increased risk of ASD in children because the timing of neural tube closure, and therefore the use of folic acid corresponds with embryogenesis

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De Almeida AJPO, de Oliveira JCPL, da Silva Pontes LV et al (2022) ROS: basic concepts, sources, cellular signaling, and its implications in aging pathways