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Vitamin B12 is a water-soluble vitamin , meaning the body typically excretes excess amounts through urine
In patients with T2DM who do not have atherosclerotic cardiovascular disease (ASCVD)/indicators of high-risk, HF, or CKD and who need to minimize hypoglycemia and/or promote weight loss, GLP-1 RAs are generally recommended as a second or third-line option as add-on to metformin therapy
The combination makes particular sense for those dealing with both Achilles problems and other soft tissue issues elsewhere
The timeframe for noticing an improvement can vary from person to person
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