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Abbreviations ( Cyp11a1 ) Cytochrome P450 family 11 subfamily a polypeptide 1 (ELISA) Enzyme Linked Immunosorbent Assay (FSH) Follicle-Stimulating Hormone (GnRH) Gonadotropin-Releasing Hormone (LC) L-carnitine, (LH): Luteinizing Hormone (MDA) Malondialdehyde (MSG) Monosodium Glutamate (ROS) Reactive Oxygen Species ( Star ) Steroidogenic Acute Regulatory protein (TAC) Total Anti-oxidant Capacity ( Hsd17b3 ) 17-Hydroxysteroid dehydrogenase-3 Authors contributions FK, FG, and MHM did all the experiments, statistical analyses, and figure preparations

This formulation allows for absorption independent of intrinsic factors , making it ideal

The data presented show that, in mouse models, N-104 may suppress autoimmunity while simultaneously promoting beta cell regenerationmarking a new potential DMT worth exploring further