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Pica test serves as an indirect indicator of nausea/malaise in non-vomiting species (e.g., mice), assessed through the ingestion of kaolin clay, a non-nutritive substance that mice instinctively consume as a response to gastrointestinal discomfort 77

It is not a drug or supplement and must not be used for human or veterinary purposes or any form of consumption.

Urine protein measurements can be standardized to the amount of creatinine in the urine (to compensate for differences in urine concentration) and are expressed as urine protein to creatinine ratio or urine albumin to creatinine ratio (UACR)

However, many clinicians report that imiquimod is useful for treating IEC