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Retrieved from Ryan, D

The fitted data of the recovery curve were visualised with GraphPad Prism

Microbiota depletion by different cocktails of antibiotics (ABX) or in germfree (GF) mice was reported to impaired the thermogenic capacity of BAT by decreasing the expression of UCP1 (94)

The mechanisms likely include: Chronic inflammation from excess adipose tissue Hormonal imbalances (particularly estrogen and insulin) Immune system dysfunction Cellular stress and DNA damage By addressing obesity, GLP-1 agonists may interrupt these cancer-promoting pathways