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The authors write that Louwagies case report (and others) should not detract from the substantial value of GLP-1 based therapies, but they do speak yet again to the importance of individualized therapy

Glucagon receptor activation promotes thermogenesis, increases energy expenditure, and mobilizes fat stores from the liver

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Sauna Use & Nature As noted in a 2021 systematic review, thermal stress from sauna exposure induces adaptive responses that improve endothelial function, nitric oxide bioavailability, insulin sensitivity, and autonomic balance, contributing to reduced cardiovascular risk (28)