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In the sensitivity analysis of this study, once-weekly semaglutide showed a greater increase in quality-adjusted life expectancy (+ 0.74 QALYs for semaglutide 0.5 mg, + 0.95 QALYs for semaglutide 1.0 mg) compared with PEG-loxenatide 0.2 mg when the larger disutility value in BMI was applied

Over-the-counter supplements operate under different regulatory frameworks with fewer manufacturing requirements and no obligation to prove efficacy in human studies

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This tracking capability ensures accountability and enables rapid response to any quality concerns that may arise