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HYPOGLYCAEMIA: Low risk as monotherapy or with metformin (glucose-dependent mechanism)

Sci Rep 6 , 37596 (2016)

Therefore, we doubted the validity of its results and significance of clinical practice and aimed to use the method recommended by the Cochrane Collaboration to perform a meta-analysis of RCTs with high quality

377,378,379 IDH1 mutations in human cancers favor consuming the NADPH for 2-HG synthesis at the expense of other NADPH-requiring pathways essential for cell viability even when NADPH is limiting