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For the first time, large numbers of patients are achieving sustained, clinically-significant weight loss, often 15 to 20 per cent of body weight in under a year

The number of glaucoma cases associated with an actually elevated IOP varies significantly across glaucoma subtypes, and many glaucoma patients progress to blindness despite low IOPs and/or are refractory to IOP-lowering treatments (Dielemans et al., 1994

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