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Weight Loss and the Emotional Impact Significant weight loss, as evidenced by my own 120-pound reduction from 285 pounds over 19 months through GLP-1 use, cardio, lifting, and food management, can trigger significant psychological and hormonal changes that can impact emotional well-being (Ingels & Zizzi, 2018)

Alas, you can add one more unpleasant side effect to the list: persistent and particularly malodorous belching

Ask your PBM what rebates they are securing and whether they are passing them through

Disturbances in the cholinergic system are likely due to alterations in acetylcholine metabolism with a significant relationship to AD-like symptoms in DS adults since an impaired acetylcholine metabolism has been reported in the brains of individuals with AD