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Description

GLP-1 receptor agonists mimic the glucagon-like peptide-1 hormone which regulates appetite and blood sugar levels

doi: 10.1146/annurev.pharmtox.010909.105600 43 YoussefLARebbaaAPampouSWeisbergSPStockwellBRHodEAet al

It runs for 80 weeks (the longest in the program), enrolls a general obesity population without type 2 diabetes, and is designed to be the direct apples-to-apples analogue of SURMOUNT-1 (tirzepatide) and STEP-1 (semaglutide)