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First, the two core mechanism papers establishing the HGF/c-Met story (Kawas 2012, PMID 22129598

A key strength of neurobiophysics is its emphasis on experimental control

Hepatic cytochrome P450 enzyme activity and renal clearance efficiency both decline with age, which could theoretically extend the dihexa half life in older subjects, but specific pharmacokinetic data stratified by age are not published for dihexa

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