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It has been shown to inhibit apoptosis and cell death in primary cardiomyocyte and endothelial cell cultures (352), to have varying effects on the proliferation of various prostate carcinoma cell lines (353), to inhibit isoproterenol-induced lipolysis in rat adipocyte cultures (354), and to induce hypotension and bradycardia when injected into the nucleus tractus solitarii of rats (355)

The proposed mechanism most often cited involves copper transport, modulation of growth-factor signaling, and effects on the extracellular matrix

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