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Fe 3+ , Cu 2+ ) it is known to directly target cellular lipids, proteins, nucleic bases, causing DNA base modification or fragmentation[5]

Solution structure of the microtubuletargeting COS domain of MID1

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Stage III (72-96 hours) = Maximal stage of hepatotoxicity = Hepatic failure Clinical features Recurrence of systemic symptoms (anorexia, nausea, vomiting, malaise) Emerging signs & symptoms of hepatic failure : Encephalopathy, jaundice, coagulopathy, hypoglycemia, lactic acidosis, shock