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This was followed up one year later with positive results from an experiment involving rabbits with collagenase-induced knee osteoarthritis except the combination of AOD-9604 AND hyaluronic acid were more effective in cartilage regeneration than either compound alone

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Substances that are absorbed through the buccal route go directly into the systemic circulation and this eliminates disadvantages imposed by oral intake, such as the decreased ability of GSH to pass through the gastrointestinal tract as an intact molecule

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