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Difference Between GLP-1 Receptor Agonists and Other Diabetes Medicines How They Work GLP-1 Receptor Agonists mimic a natural hormone (glucagon-like peptide-1) to increase insulin only when needed, suppress glucagon (which raises blood sugar), and slow digestion to help with weight control

Non-drug RLS treatments may include hot baths, heating pads or ice packs applied to the legs, good sleeping habits and leg massages

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For anyone with diabetes, the safest approach is to keep your GP or diabetes team in the loop, so your B12, your blood sugar control and your nerve health are all being looked at together rather than in isolation