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Blood markers may change before nerve symptoms improve, and long-standing neurologic symptoms may take longer to assess

Neurological symptoms like tingling or numbness could take several weeks or months of consistent treatment to improve

Wash hands thoroughly and consider using nitrile gloves

Am J Phys Heart Circ Phys 298:H2174H2191 Wieczor R, Gadomska G, Ruszkowska-Ciastek B, Stankowska K, Budzynski J, Fabisiak J, Suppan K, Pulkowski G, Rosc D (2015) Impact of type 2 diabetes on the plasma levels of vascular endothelial growth factor and its soluble receptors type 1 and type 2 in patients with peripheral arterial disease