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Studies have demonstrated that specific AAs can bind and activate G-protein-coupled receptors, which in turn induce lysosomal localization and activation of mTORC1 (89)

Nucleic Acids Res 33:e21 Eoh H, Rhee KY (2014) Methylcitrate cycle defines the bactericidal essentiality of isocitrate lyase for survival of Mycobacterium tuberculosis on fatty acids