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This article examines the evidence surrounding B12 supplementation, optimal timing for those who require it, and safe, effective use within the context of metabolic health and weight management

The intragastric administration route used in Sun 2021 reflects the BBB-permeability and oral-bioavailability profile characterized for Dihexa in the McCoy 2013 pharmacokinetic work

Authors were contacted if not enough data was included in the original manuscript for analysis, for clarification of terms or to confirm whether the article contained data previously published by the same research group

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