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Abdominal pain or upset stomach Appetite loss Diarrhea, nausea, or vomiting Coma Seizures May Support Liver Health May Improve Lung Health Because of this benefit, research suggests that NAC may help with chronic respiratory conditions by making it easier to breathe. May Boost Mental Health Studies on mental health conditions such as obsessive-compulsive disorder (OCD), substance use disorders, and mood disorders like depression and bipolar disorders suggest NAC may modulate glutamate signaling one of the brains key chemical messengers and reduce oxidative stress, says Holland