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Results include 7.5% reduction in body weight from baseline at day 36 Weight loss continued to at least 4 weeks after last dose administered MET-097, incorporating Metseras HALO platform technology, achieved 380-hour half-life Potential for monthly dosing and dosing regimens without titration Metsera launching Phase 2b trials in Q4 2024, with data anticipated in first half of 2025 NEW YORK--(BUSINESS WIRE)--Metsera, Inc., a clinical-stage biopharmaceutical company accelerating the next generation of medicines for obesity and metabolic diseases, today announced positive topline results from the Phase 1 clinical trial of MET-097, an ultra long-acting injectable, fully-biased GLP-1 receptor agonist

29 29 29 30 31 Additionally, a decrease in the concentration of triglycerides and VLDL cholesterol was observed in subjects with PCOS

If you are a candidate for GLP 1 therapy and your hormone levels show imbalance, your provider may discuss whether MHT is appropriate and safe for you