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l-Arginine, which is converted to nitric oxide via nitric oxidase, stimulates the production of GLP-1, and dysregulation of l-arginine in obese patients leads to increased risk of airway inflammation and bronchoconstriction [85]

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DSIP is a neuropeptide with a broader, less clearly defined activity profile that, in research, is linked not only to sleep but also to stress and cortisol regulation