References (For Scientific Context) Benoist CC et al., , 2014 Journal of Pharmacology and Experimental Therapeutics Wright JW et al., , 2015 Journal of Alzheimers Disease Sun X et al., , 2021 Brain Sciences Reviews There are no reviews yet
In preclinical cell culture assays measuring dendritic arborization and synaptic outgrowth, Dihexa demonstrated neurotrophic activity estimated to be up to seven orders of magnitude 1,000,000 times more potent than Brain-Derived Neurotrophic Factor (BDNF) on a molar basis
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However, when the mice were treated with Dihexa, levels of both IL-1-beta and TNF-alpha were found to significantly decrease