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As we age, stomach acid production can decline (atrophic gastritis), which makes it harder to extract B12 from food or pills

HA injections reported that PRP patients had better pain relief and functional improvement at 6 and 12 months post-treatment , whereas HA benefits diminished after 6 months (PMID: 30212925)

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However, factors such as poor diet, environmental pollution, chronic stress and ageing can compromise the body's ability to produce and maintain adequate glutathione levels