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Indications: Overactive bladder Common symptoms include urgency, urinary incontinence, and increased urinary frequency Side Effects: increased blood pressure / hypertension urinary tract infections nasopharyngitis constipation Pharmacokinetics: taken orally by tablet, 25 mg once daily metabolized via multiple pathways involving dealkylation, oxidation, glucuronidation, and hydrolysis 6-12% is eliminated unchanged by the kidney, involving glomerular filtration and active secretion that is dose-dependent Drug Interactions: mirabegron is a moderate inhibitor of CYP2D6 Notes: the estimated Walmart cost for Mybetriq oral 50mg tablets is ~$440 for a supply of 30 tablets (GoodRx.com

pylori strains, including the virulent one, ATCC 700824

From here, your prescriber will titrate you depending on how you react, the intent being to achieve your maintenance dose over a number of weeks

Pacini, B