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Common, expected injection site reactions include: Redness or erythema at the injection site Mild swelling or oedema Bruising or haematoma formation Itching or mild discomfort Small, firm nodules beneath the skin (particularly if sites are not rotated) These reactions are typically self-limiting

A second Phase I study in adults with diabetic kidney disease reported a D+Q dependent clearance of senescent adipose and skin cells and reduced SASP within 11 days of treatment (106)