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The primary role of glutathione is to protect our cells from oxidative stress

Activation of IR and IGF1R by their cognate ligands initiates a cascade of phosphorylation events beginning with a conformational change of the receptors leading to autophosphorylation and the recruitment and phosphorylation of substrates such as IRS-1 and Shc proteins (46)

In addition to its antioxidant activity, GSH has a variety of other functions including regulation of mitochondrial function, iron metabolism, immune cell polarization, cytokine production, and inflammatory signaling (Lu, 2013