2 months on glp 1 Years(well 25 months?) GLP-1 Medication- thought I would share— : r/Zepbound Second month in! : r/glp1

First new growth visible

(33409766) Secondary hyperammonemia 2/2 disorders causing urea cycle substrate deficiency : Disorders in the carnitine cycle or pyruvate dehydrogenase complex, fatty acid beta-oxidation, pyruvate carboxylase deficiency, pyrroline-5-carboxylate synthetase deficiency, HHH syndrome, lysinuric protein intolerance, hyperinsulinemia-hyperammonemia syndrome, and liver failure

It is known that SNVs in the ABCB1 gene can directly affect the uptake of VPA by the brain and also the excretion (efflux) of VPA from the brain into the blood

Albumin-bound Pt(IV)-resveratrol systems demonstrated 12-fold increased tumor accumulation through enhanced permeability and retention (EPR) effects, while glycyrrhizin-modified variants achieved liver-specific targeting in hepatocellular carcinoma models [112]