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Timeline: When Semaglutide Nausea Usually Improves Most people experience peak nausea in the first 2 to 4 weeks after starting semaglutide, especially if they jump to a higher dose too quickly

However, patients should contact their healthcare provider if they experience: Severe pain or swelling that worsens over time Signs of infection such as warmth, pus, or fever Large lumps or hard nodules that do not improve Allergic reactions like rash, difficulty breathing, or swelling of the face Prompt medical attention can prevent complications and ensure safe use of tesamorelin