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[11] Foundayo (Oral GLP-1 Now Available) Eli Lilly's Foundayo (orforglipron) received FDA approval April 1, 2026the first oral daily GLP-1 for weight loss

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However, these agents increase risk of intra-operative pulmonary aspiration according to a case report secondary to delayed emptying and presence of gastric residues despite fasting (108, 108) To prevent these events, the recent recommendations from the American Society of Anesthesiology guidelines suggest discontinuing GLP-1 receptor agonists 1 day prior in patients on daily dosing and 1 week prior in patients on weekly injection dosing (108)

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