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This combined action has shown to be exceptionally powerful in clinical studies

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In the fish, creatine plus phosphocreatine concentrations in skeletal muscle were 1315, 1316, and 112125 times those in the proximal intestine, kidneys, and liver, respectively, whereas GSH concentrations in the liver were 3.23.5, 5.36.6, and 911 times those in the proximal intestine, kidneys, and skeletal muscle, respectively